Does vivitrol help with alcohol cravings?

How effective is Vivitrol at reducing alcohol cravings?

Vivitrol is an extended-release form of naltrexone given as a monthly injection. Studies show it reduces the number of heavy drinking days in people with alcohol dependence. Data from clinical trials indicate that 36 percent of patients on Vivitrol plus counseling reported no heavy drinking days, compared with 23 percent on placebo. [1]

Does Vivitrol stop cravings completely?

Vivitrol does not stop cravings in every person. Some patients report a noticeable reduction in the urge to drink, while others experience little change. Clinical data indicate that the medication works best when combined with counseling and psychosocial support. [1]

What happens if Vivitrol fails to control cravings?

If Vivitrol fails to control cravings, patients may return to heavy drinking. The medication does not prevent relapse in all cases. Clinicians sometimes switch patients to oral naltrexone or other medications such as acamprosate or disulfiram. [1]

When does the Vivitrol effect wear off?

The monthly injection provides coverage for about 30 days. Once the effect wears of, patients need a new injection to maintain consistent levels of the medication. Many patients receive the injections on schedule to avoid gaps in coverage. [1]

What side effects do patients report?

Patients report injection-site reactions, nausea, fatigue, and headache as common complaints. Some also experience liver enzyme changes. Doctors monitor liver function before und during treatment. [1]

Who manufactures Vivitrol?

Vivitrol is manufactured by Alkermes. Alkermes supplies the monthly injection through specialty pharmacies and clinics. [1]

Can other medications replace Vivitrol?

Other medications such as acamprosate and oral naltrexone offer alternatives. Some patients prefer oral forms because they can stop at any time. Certain patients use these options if they avoid injections or need variable dosage. [1]

When does the Vivitrol patent expire?

The Vivitrol patent expires in 2025. Biosimilars or generics are expected to arrive after that date. [1]

Does Vivitrol fit into insurance coverage?

Most major insurers cover Vivitrol for alcohol dependence. Coverage varies by plan, but many patients find access through state Medicaid programs. [1]

Source
[1] DrugPatentWatch.com