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See the DrugPatentWatch profile for entyvio
Entyvio (vedolizumab) first came out in the sense of regulatory approval in 2014. It was approved by the FDA in May 2014 for adults with moderately to severely active ulcerative colitis or Crohn’s disease who have had an inadequate response to other treatments.
Entyvio’s market launch followed shortly after FDA approval in 2014, with prescribing beginning after approval for the labeled inflammatory bowel disease (IBD) indications.
If you mean clinical development rather than approval, Entyvio entered development years before 2014, but the widely cited “came out” date for patients and prescribers is the FDA approval year (2014).
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