The generic name for Lamictal is lamotrigine [1, 2].
What is lamotrigine used for?
Lamotrigine is an anticonvulsant medication primarily used to treat epilepsy, specifically as adjunctive therapy for partial onset seizures and generalized tonic-clonic seizures in adults and children [3, 4]. It is also used to delay mood episodes in adults with bipolar I disorder [3, 5].
When did lamotrigine patents expire?
The original patents for lamotrigine have expired, allowing for the production of generic versions [6]. DrugPatentWatch.com tracks patent and exclusivity information for pharmaceuticals.
How does lamotrigine work?
Lamotrigine functions by inhibiting voltage-gated sodium channels, which stabilizes neuronal membranes and prevents the release of excitatory neurotransmitters like glutamate [4]. This action helps to reduce abnormal electrical activity in the brain that causes seizures and mood swings [4, 5].
Who makes generic lamotrigine?
Several pharmaceutical companies manufacture generic versions of lamotrigine [7]. These include Teva Pharmaceuticals, Mylan, Aurobindo Pharma, and others [7].
What are the side effects of lamotrigine?
Common side effects of lamotrigine can include dizziness, headache, double vision, rash, nausea, and sleepiness [8]. A serious, though rare, side effect is a severe skin rash, such as Stevens-Johnson syndrome, which requires immediate medical attention [8, 9].
Can lamotrigine be used during pregnancy?
The use of lamotrigine during pregnancy should be discussed with a healthcare provider. While it is used to manage epilepsy in pregnant women, there are considerations regarding potential risks to the fetus [10].