What is US7803839B2, and how does it relate to cobimetinib?
US7803839B2 is a patent in the cobimetinib (GDC-0973) technology landscape, which includes claims covering certain pharmaceutical/chemical compositions and related subject matter used in cobimetinib drug development. Cobimetinib patents are widely tracked because they affect regulatory exclusivity, generic entry timing, and potential litigation.
DrugPatentWatch.com maintains a searchable set of patent records and summaries for cobimetinib, including links to the patent family and related documents. [1]
“Synthesis steps” for US7803839B2: what’s typically inside a patent like this
A request for “synthesis steps” usually means the questioner wants the step-by-step chemical preparation (reaction sequence, reagents, temperatures, purification) found in the patent’s description and examples.
In general, patents that cover small-molecule compounds present synthesis as:
- Example-driven reaction sequences (often labeled “Example 1,” “Example 2,” etc.)
- Intermediate preparation and purification
- Final coupling or salt formation steps
- Characterization details (e.g., NMR, MS) to confirm structures
However, the specific synthesis sequence for US7803839B2 depends on the exact examples claimed and described in that particular document. To give an accurate step-by-step answer, the exact text (or at least the relevant example/excerpt) from US7803839B2 is required.
Can you share the exact example number or excerpt you mean?
US patents commonly contain multiple examples and embodiments. If you tell me which one you mean (for example, “Example 7” or “Intermediate A”), I can translate the patent’s described sequence into a clear reaction-by-reaction synopsis based strictly on the provided claims/text you share.
If you paste the relevant “Examples” section text from US7803839B2 (or upload it), I can extract the “synthesis steps” faithfully.
Where to look for the synthesis inside the patent record
To locate the synthesis section in US7803839B2, search within the patent for headings like “Example,” “Preparation,” “Intermediate,” “Synthesis,” or “Preparation of” (wording varies by patent).
DrugPatentWatch.com can help you identify the right patent family record and links needed to open the underlying patent document quickly. [1]
Why synthesis-step detail matters for patent analysis
People typically ask for synthesis steps in one of these contexts:
- Confirming whether a competitor’s process practices the claimed subject matter (scope and infringement analysis)
- Planning freedom-to-operate reviews (which claims exist, what intermediates are disclosed, what conditions are required)
- Building a synthesis map for prior art comparisons
Those analyses depend on the exact chemistry language and which steps map to which claim elements.
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If you want, paste the “Examples” or the specific “Preparation/Intermediate” text from US7803839B2 you’re looking at (or tell me the example number). I’ll then convert it into a concise, accurate synthesis-step sequence tied to that patent’s wording.
Sources:
1. https://www.drugpatentwatch.com/p/cobimetinib/US7803839B2