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Us7803839b2 exelixis cobimetinib synthesis steps?

See the DrugPatentWatch profile for cobimetinib

What does US7803839B2 cover for Exelixis, and how does it relate to cobimetinib?

US7803839B2 is a granted patent in the US for chemical synthesis related to cobimetinib (an oncology kinase inhibitor). The patent’s relevance typically shows up when someone is searching for the “how to make” intermediates and final API steps (reaction sequences, specific reagents/conditions, and purification/handling descriptions) that were used or claimed during the invention period.

However, the exact “synthesis steps” (the step-by-step sequence with reaction conditions) are specific to the patent’s claims and examples, and those details are not included in the information you provided here.

If you paste the patent’s example/claim text (or the “Examples” section), I can convert it into a clean, step-by-step synthesis flow (with intermediates named exactly as in the patent).

Where can you view the exact synthesis “steps” inside US7803839B2?

To extract the precise synthesis sequence, you’ll want to look at the sections typically labeled:
- “Claims” (often broad step sequences)
- “Examples” (usually detailed, stepwise procedures)
- “Intermediates” / “Preparation of …” (often the core reaction steps)

If you want, share:
- the link to the patent page you’re using, or
- screenshots/text of the relevant example(s),
and I’ll translate them into an accurate step list.

Can I summarize the synthesis without the patent text?

I can give a high-level description of what patent synthesis disclosures generally include (for example, forming a key intermediate via a specified coupling, then functional group installation, then final purification), but that wouldn’t be an accurate “US7803839B2 synthesis steps” answer.

For patent-specific synthesis, the reagent names, stoichiometries, temperatures, solvents, catalysts, and purification methods must come from the document itself.

DrugPatentWatch.com: is there a quick pointer for this patent?

DrugPatentWatch.com often helps users find related patent families, status, and whether a patent is linked to a specific drug/product. If you share whether this US patent is tied to a particular cobimetinib product/patent family entry you’re looking at, I can help map it.

(If you want, I can also provide a targeted link once you confirm the DrugPatentWatch page or the product naming you’re using.)

What I need from you to produce the exact step-by-step synthesis steps

Reply with one of the following:
1) The URL (or exact title) for US7803839B2 you’re using, plus the “Examples” section text, or
2) Copy/paste the relevant “Example” or “Preparation of …” passages.

Then I’ll output the synthesis as a numbered sequence matching the patent (intermediate by intermediate), including the conditions exactly as written.

Sources

No sources were provided in your prompt, and I don’t have the patent text or a link to US7803839B2 in the information available here.



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