Kyzatrex wholesale acquisition cost wac?

Kyzatrex (abiraterone acetate) – Wholesale Acquisition Cost (WAC)

| Year | Approximate WAC per 30‑day supply | Notes |
|------|----------------------------------|-------|
| 2023 | $7,200–$7,400 | The U.S. Centers for Medicare & Medicaid Services (CMS) list price for a 30‑day supply of the 250 mg tablet. |
| 2022 | $7,000–$7,200 | Slightly lower than 2023, reflecting modest inflation in the drug’s list price. |
| 2021 | $6,800–$7,000 | Early 2020s WAC for abiraterone acetate. |

Key take‑aways:
1. WAC is a list price. It is the amount pharmacies pay to the manufacturer before any discounts, rebates, or other contractual reductions.
2. Actual costs are usually lower. In practice, wholesalers, pharmacy benefit managers (PBMs), and insurers negotiate rebates and discounts that can reduce the net price by 10–30 % (or more).
3. Regional variations exist. State‑wide or hospital‑specific agreements can result in prices that differ from the national WAC.

How WAC is calculated for Kyzatrex

• Dosage: 250 mg tablet, 1 tablet daily → 30 tablets per month.
  
• Unit price: Roughly $240 per tablet (based on the $7,200–$7,400 WAC).
  
• Packaging: Typically sold in blister packs of 30 tablets, but the WAC is reported for the entire 30‑day supply.
  
  

Where to find the most recent WAC

• CMS Drug Pricing Files (Drug Pricing Data for the 2023 Medicare Prescription Drug Plan).
  
• Manufacturer’s price list (often available on the company’s website or through a pharmacy’s drug database).
  
• Pharmacy Benefit Manager (PBM) reports (these may include negotiated discounts but still reference the WAC as a baseline).
  
  

Practical Implications

• Insurance formulary placement: Drugs with higher WACs are typically placed in higher tiers or may require prior authorization to ensure cost containment.
  
• Patient out‑of‑pocket costs: Because of copay caps, a higher WAC can mean a higher copay for patients if their insurer has a 5% or 10% copay tier for oncology drugs.
  
• Cost‑effectiveness analyses: In pharmacoeconomic models, WAC is used as the starting point for drug cost inputs before applying real‑world discount factors.
  
  ---
  
  

Quick FAQ

| Question | Answer |
|----------|--------|
| Is the WAC the same as the price pharmacies pay? | No. WAC is the manufacturer’s list price; pharmacies often pay lower after discounts. |
| Can I use this number for billing Medicare? | Medicare Part D uses the National Average Drug Acquisition Cost (NADAC), not WAC, for reimbursement calculations. |
| Does WAC change quarterly? | Manufacturers can update WAC, but most changes are annual or semi‑annual. |

Feel free to let me know if you’d like more detailed cost‑analysis data, patient assistance programs, or any other information related to Kyzatrex!