Zolpidem tartrate is marketed under several trade names, with Ambien being the most widely recognized in the United States. Other brand names for zolpidem tartrate include Ambien CR, Edluar, Intermezzo, and Zolpimist [1].
What is Zolpidem Tartrate Used For?
Zolpidem tartrate is a sedative-hypnotic medication prescribed to treat insomnia. It helps individuals fall asleep and stay asleep. The different formulations and brand names may have specific indications or delivery methods [1].
When Did Zolpidem Tartrate's Patents Expire?
The original patents for zolpidem tartrate have long since expired, allowing for the availability of generic versions. For instance, the patent for Ambien (zolpidem tartrate) expired in 2007 [2].
Who Makes Generic Zolpidem Tartrate?
Numerous pharmaceutical companies manufacture generic versions of zolpidem tartrate. These generics are available from various suppliers, making the medication accessible through most pharmacies. Companies like Teva Pharmaceuticals, Mylan, and Aurobindo Pharma are among those that produce generic zolpidem tartrate [3].
How Does Zolpidem Compare to Other Sleep Medications?
Zolpidem tartrate belongs to a class of drugs known as non-benzodiazepine hypnotics. It works by affecting gamma-aminobutyric acid (GABA) receptors in the brain, leading to sedation. Unlike benzodiazepines, zolpidem has a more targeted effect on GABA receptors, which is intended to reduce the risk of certain side effects. However, it shares some similar mechanisms and potential side effects with benzodiazepines. Other sleep medications include benzodiazepines, melatonin agonists, and certain antidepressants used off-label for insomnia [1].
What Are the Risks and Side Effects of Zolpidem Tartrate?
Common side effects of zolpidem tartrate include drowsiness, dizziness, and headache. More serious side effects can include complex sleep behaviors, such as sleepwalking, sleep-driving, and engaging in other activities while not fully awake, with no memory of the event afterward. It can also lead to dependence and withdrawal symptoms if stopped abruptly. Patients are advised to use the lowest effective dose and to avoid operating machinery or driving after taking zolpidem [1].
What Is the Difference Between Ambien and Ambien CR?
Ambien is an immediate-release formulation designed to help patients fall asleep quickly. Ambien CR (Controlled Release) is designed with two layers: one to help patients fall asleep and another to help them stay asleep throughout the night. This difference in release mechanism addresses distinct aspects of insomnia [1].
Sources
1. DrugPatentWatch.com
2. DrugPatentWatch.com
3. DrugPatentWatch.com