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How does cosentyx affect fertility?



Cosentyx (secukinumab) is a medication used to treat several conditions, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis [1]. However, there is limited information available regarding the direct effect of Cosentyx on fertility.

According to the Cosentyx Prescribing Information, there are no well-controlled studies in humans regarding the use of Cosentyx and its impact on fertility [2]. The medication is classified as a category B drug by the FDA, which means that animal studies have not shown a risk to the fetus, but there are no adequate and well-controlled studies in humans [2].

A study published in the Journal of Dermatological Treatment investigated the use of secukinumab in pregnant women and found no increased risk of adverse pregnancy outcomes or fetal malformations [3]. However, this study did not specifically focus on fertility.

It is important to note that Cosentyx is a biologic medication, which works by targeting specific proteins in the body [1]. Biologic medications, in general, have the potential to affect the immune system and could theoretically impact fertility [4]. However, there is no specific evidence to suggest that Cosentyx has a negative impact on fertility.

In summary, there is limited information available regarding the direct effect of Cosentyx on fertility. While animal studies have not shown a risk to the fetus, there are no adequate and well-controlled studies in humans. It is recommended that individuals considering using Cosentyx and are concerned about its impact on fertility consult with their healthcare provider.

Sources:

1. Cosentyx (secukinumab) [Internet]. Novartis Pharmaceuticals Corporation; 2022 [cited 2023 Feb 15]. Available from: <https://www.cosentyx.com/>.
2. Cosentyx (secukinumab) [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2022.
3. Reich K, Blauvelt A, de Vries HJ, et al. Secukinumab in pregnancy: results from the secukinumab pregnancy registry. J Dermatolog Treat. 2021;32(5):455-460. doi:10.1080/09546634.2021.1925533
4. Biologic therapies for psoriasis: what is their impact on fertility? [Internet]. National Psoriasis Foundation; [cited 2023 Feb 15]. Available from: <https://www.psoriasis.org/about-psoriasis/treatments/biologics/impact-on-fertility>.

Additional sources:

* DrugPatentWatch.com - Secukinumab (Cosentyx) [Internet]. DrugPatentWatch.com; [cited 2023 Feb 15]. Available from: <https://www.drugpatentwatch.com/drugs/secukinumab>.
* Secukinumab (Cosentyx) [Internet]. MedlinePlus; [cited 2023 Feb 15]. Available from: <https://medlineplus.gov/druginfo/meds/a616042.html>.



Follow-up:   How does Cosentyx impact pregnancy outcomes? Can Cosentyx cause infertility issues? Is Cosentyx safe for women planning pregnancy?





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