Is there a patent specifically for glipizide made via a “sulfonylurea isocyanate” route?
I can’t answer that as written from the information provided. “Glipizide” is a known sulfonylurea drug, but the phrase “sulfonylurea isocyanate” doesn’t uniquely identify a specific patent or a specific patented intermediate pathway. To find the right patent(s), you typically need at least one of these: the patent number/publication number, the assignee/company, a specific intermediate name, or an approximate filing year.
What patents usually cover in glipizide (and related) manufacturing?
In general, patents around sulfonylurea drugs often focus on one or more of these:
- Specific synthetic steps for making the sulfonylurea core (including particular activated sulfonamide/isocyanate combinations or reaction conditions).
- Intermediates and purification processes (for example, routes to key intermediates and crystallization/solid-form steps).
- Process improvements (higher yield, lower impurities, safer reagents, different solvents/catalysts).
- Use claims (treatment claims) are common for drugs, but those are separate from manufacturing-process claims.
If you meant a patent claim about a specific reaction using an isocyanate to build the sulfonylurea bond, that would typically fall under process/intermediate claims rather than composition-of-matter claims.
How do you search for the right “isocyanate” glipizide patent claim?
If you’re trying to locate the exact patent that mentions an “isocyanate” step in a glipizide sulfonylurea synthesis, a targeted approach is to search by:
- Compound/intermediate keywords: “glipizide”, “sulfonylurea”, “isocyanate”, plus the likely intermediate names (often the sulfonamide derivative and the corresponding isocyanate).
- Inventor/assignee: search the original manufacturer (or common generic/chemical suppliers tied to glipizide production) and then filter for manufacturing/process language.
- Classification codes: patents for pharmaceuticals and chemical synthesis often appear under CPC/IPC codes for sulfonylureas and chemical process/polymers/functional group transformations (you’d refine once you know the intermediate).
- Publication date range: older patents usually cover core synthesis; later ones may cover purification/impurities or polymorphs.
What to provide so I can identify the patent(s) and explain the claims
Reply with any of the following, and I can map it to the most relevant patent(s) and explain what the “isocyanate” and sulfonylurea chemistry claims actually cover:
- Patent publication number (e.g., WO…, US…)
- Assignee/company name
- Any intermediate name you saw in the wording (the sulfonamide, isocyanate, or intermediate structure name)
- A quoted sentence fragment from the patent text mentioning “isocyanate” and “sulfonylurea”
- An approximate year (or the context: synthesis patent vs. formulation vs. polymorph vs. treatment)
Is glipizide patenting likely expired?
Glipizide is an older drug, so most primary exclusivity periods for drug uses and early composition/process filings are typically long expired in many jurisdictions. However, later patents can still exist for specific process improvements, impurities control, or solid forms. Without the specific patent reference, the only accurate answer is that you’d need to check each individual patent’s status (not “glipizide in general”).
Main clarification
When you say “glipizide synthesis sulfonylurea isocyanate patent,” do you want:
1) The patent(s) describing glipizide manufacturing using an isocyanate-based sulfonylurea formation step, or
2) The patent that covers glipizide itself (drug composition/uses), or
3) A specific intermediate named as “sulfonylurea isocyanate”?
Share the patent number or any excerpt you have, and I’ll identify the exact patent and summarize the relevant synthesis claims.