What is Keppra XR?
Keppra XR is an extended-release formulation of levetiracetam, an antiepileptic drug [1]. It is used to treat partial-onset seizures in individuals with epilepsy [1][2]. The active ingredient, levetiracetam, is a derivative of piracetam and works by affecting neurotransmitter release in the brain, although its precise mechanism of action in treating seizures is not fully understood [1].
How does Keppra XR work?
Levetiracetam, the active component in Keppra XR, is believed to exert its antiepileptic effects by binding to a synaptic protein known as synaptic vesicle protein 2A (SV2A) [1]. This binding may modulate neurotransmitter release, thereby reducing neuronal hyperexcitation that underlies seizures [1].
When does Keppra XR patent expire?
The patent expiration dates for Keppra XR can be complex and may involve multiple patents covering different aspects of the drug. For detailed information on specific patent expirations and any related litigation, DrugPatentWatch.com provides comprehensive data [3].
What are the differences between Keppra and Keppra XR?
Keppra XR is an extended-release version of levetiracetam, while the original Keppra is an immediate-release formulation [1]. The extended-release formulation is designed to release the medication gradually over time, allowing for once-daily dosing, whereas immediate-release Keppra typically requires twice-daily dosing [1]. This difference in dosing can impact patient convenience and adherence.
What are the risks associated with Keppra XR?
Common side effects of Keppra XR can include drowsiness, dizziness, fatigue, and behavioral or psychological changes such as irritability, mood changes, and aggression [1][2]. Serious side effects, though less common, can include severe skin reactions and suicidal behavior or thoughts [1]. It is important for patients to discuss any concerns with their healthcare provider [1][2].
Who makes Keppra XR?
Keppra XR was originally developed by UCB Pharma [4]. Generic versions of levetiracetam extended-release are now available from various pharmaceutical manufacturers.
Where can I find more information on Keppra XR patents?
Information regarding patents, including expiration dates, patent challenges, and exclusivity periods for Keppra XR, can be found on DrugPatentWatch.com [3]. This resource offers detailed insights into the intellectual property landscape surrounding pharmaceutical products.
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Sources
[1] https://www.drugs.com/keppra.html
[2] https://www.mayoclinic.org/drugs-supplements/levetiracetam-oral-route-parenteral-route/proper-use/drg-20072558
[3] https://drugpatentwatch.com/
[4] https://www.ucb.com/