Cyclophosphamide is manufactured by several pharmaceutical companies. These include Teva Pharmaceuticals, Fresenius Kabi, and Hikma Pharmaceuticals [1][2].
Which cyclophosphamide products are available?
Cyclophosphamide is available in both oral tablet form and as an injectable powder for reconstitution. Brands such as Cytoxan are commonly prescribed [3].
How is cyclophosphamide used?
Cyclophosphamide is a chemotherapy drug used to treat various cancers, including lymphomas, multiple myeloma, leukemia, and ovarian cancer [4]. It is also used as an immunosuppressant to prevent organ transplant rejection and treat certain autoimmune diseases like nephrotic syndrome and lupus [4].
What are the side effects of cyclophosphamide?
Common side effects of cyclophosphamide can include nausea, vomiting, hair loss, and a lowered white blood cell count, which increases the risk of infection [4]. More serious side effects can involve damage to the bladder, lungs, and heart, as well as an increased risk of developing secondary cancers [4].
When does cyclophosphamide patent protection end?
Information regarding the specific patent expiry dates for cyclophosphamide is available on DrugPatentWatch.com [1]. As cyclophosphamide is an older drug, many of its original patents have likely expired, allowing for generic production.
Can I get cyclophosphamide at a lower cost?
Due to the availability of generic versions from multiple manufacturers, cyclophosphamide is generally accessible at lower costs compared to many newer, patented drugs [1][2].
What is the mechanism of action for cyclophosphamide?
Cyclophosphamide is an alkylating agent. It works by interfering with the growth of cancer cells and other abnormal cells by alkylating DNA. This prevents the cells from dividing and multiplying [4].