Can I drink wine while taking Simponi (golimumab)?
Simponi (golimumab) is an immunosuppressing biologic. The information provided here does not specify whether drinking wine is allowed or restricted with Simponi. Because biologics affect the immune system, alcohol safety is usually approached case-by-case, especially if you also have liver disease, hepatitis, or drink heavily.
If your clinician has not given you specific limits, the safest general approach is to avoid binge drinking and to discuss moderate alcohol intake with your prescribing doctor.
Does wine increase the risk of infections with Simponi?
Simponi can increase susceptibility to infections because it dampens parts of the immune response. Alcohol can also impair immune function in higher amounts. Together, this raises the practical concern that heavy drinking could make infections more likely or harder to manage, which is why clinicians often advise limiting alcohol while on immunosuppressive therapy.
What if I also take steroids or methotrexate with Simponi?
Many people on Simponi also use other meds for inflammatory conditions. Alcohol advice can change depending on the other drugs:
- If you take methotrexate, alcohol is typically more restricted because of liver-risk concerns.
- If you take other immunosuppressants or frequent steroids, infection risk and safety planning may also be stricter.
If you tell me what other medications you’re on, I can help you think through the usual medication-specific concerns to ask your doctor about.
Is wine a problem for liver health or hepatitis?
Alcohol matters more if you have any of the following:
- Liver disease (including cirrhosis or elevated liver enzymes)
- Chronic hepatitis B or C (relevant because some immunosuppressing therapies can reactivate hepatitis)
- A history of alcohol-related liver problems
In those situations, your prescriber may recommend avoiding alcohol entirely or setting strict limits.
What should I do if I feel sick after drinking?
Seek medical advice promptly if you develop signs of infection while on Simponi, regardless of alcohol (examples include fever, chills, worsening cough, burning with urination, skin infections). If you have recently been drinking and symptoms start, tell the clinician how much you drank and when symptoms began.
How much is “moderate” to ask about?
Without your medical history, a precise amount can’t be given. A common safety question to ask your clinician is: “What limit is safe for me—considering Simponi, any other medications, and my liver/infection risk?” Your answer can differ if you have liver disease or take methotrexate.
If you share (1) your dose of Simponi and how often you take it, (2) your other meds, and (3) whether you have liver disease/hepatitis or prior infection issues, I can tailor what to ask your doctor and what risks to prioritize.