The trade name for diclofenac sodium is Voltaren [1].
What other names is diclofenac sodium known by?
Diclofenac sodium is also marketed under various brand names globally, including Cataflam, DFC, Difene, Duralenol, Fenflammer, Gen-Diclo, Movatec, Nacflex, Nantene, Olfen, Pennsaid, Rheumatec, Rhusal, and Surgam [2].
How does Voltaren work?
Voltaren, containing diclofenac sodium, is a nonsteroidal anti-inflammatory drug (NSAID) [3]. It works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins. Prostaglandins are chemicals in the body that contribute to inflammation, pain, and fever [4]. By reducing prostaglandin synthesis, diclofenac sodium alleviates these symptoms [3][4].
What conditions is Voltaren used to treat?
Voltaren is prescribed to treat mild to moderate pain and inflammation associated with various conditions. These include osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, menstrual pain, and other types of pain such as back pain, muscle aches, and dental pain [3].
What are the potential side effects of Voltaren?
Common side effects of diclofenac sodium can include gastrointestinal issues such as stomach pain, nausea, vomiting, diarrhea, and constipation. Other potential side effects include dizziness, headache, rash, and fluid retention [5]. Serious side effects, though less common, can include gastrointestinal bleeding, heart attack, stroke, and severe allergic reactions [5][6].
Are there different formulations of diclofenac sodium?
Yes, diclofenac sodium is available in various formulations, including oral tablets, extended-release tablets, suppositories, and topical gels, patches, and solutions for localized pain relief [3][7].
What is the typical dosage for Voltaren?
Dosage for Voltaren varies depending on the specific condition being treated and the formulation used. For example, oral formulations for arthritis may range from 75 mg to 150 mg per day, divided into multiple doses. Topical formulations are applied directly to the skin over the affected area [3]. It is crucial to follow a healthcare provider's instructions for dosage and administration.
What are the risks associated with NSAIDs like diclofenac sodium?
NSAIDs, including diclofenac sodium, carry risks such as stomach ulcers and bleeding, increased risk of heart attack and stroke, kidney problems, and high blood pressure [6]. These risks may be higher with long-term use or in individuals with pre-existing health conditions [5][6].
When does the patent for diclofenac sodium expire?
Diclofenac sodium is an older medication, and its primary patents have long since expired, allowing for the widespread availability of generic versions [8].
Who are the manufacturers of diclofenac sodium products?
Numerous pharmaceutical companies manufacture generic diclofenac sodium products. Brand-name products like Voltaren are produced by GSK (GlaxoSmithKline) [1].
How does diclofenac sodium compare to other pain relievers?
Diclofenac sodium is an NSAID, similar in mechanism to ibuprofen and naproxen, and is generally considered more potent than aspirin [4]. Compared to acetaminophen (Tylenol), which primarily targets pain and fever but has minimal anti-inflammatory effects, diclofenac sodium is more effective for inflammatory pain [4][9].
Can I take Voltaren if I have certain medical conditions?
Individuals with a history of stomach ulcers or bleeding, heart disease, kidney disease, liver disease, or high blood pressure should use diclofenac sodium with caution and only under the guidance of a healthcare professional [5].
Sources:
[1] https://www.drugpatentwatch.com/brands/voltaren
[2] https://www.drugpatentwatch.com/generic/diclofenac-sodium
[3] https://www.nhs.uk/medicines/diclofenac-oral/
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097341/
[5] https://www.nhs.uk/medicines/diclofenac-oral/side-effects/
[6] https://www.ema.europa.eu/en/documents/referral/diclofenac-article-31-referral-questions-answers_en.pdf
[7] https://www.webmd.com/drugs/2/drug-16681/diclofenac-oral/details
[8] https://www.drugpatentwatch.com/reports/diclofenac-sodium
[9] https://www.nhs.uk/medicines/paracetamol-how-to-take/