What is rizatriptan benzoate?

Rizatriptan benzoate is a prescription migraine medication. It is the benzoate salt form of rizatriptan and is sold under brand names like Maxalt.

Key points:
- Drug class: Triptan (a selective 5-HT1B/1D receptor agonist).
- What it does: It helps treat an acute migraine attack by causing constriction of cranial blood vessels and reducing the release of inflammatory chemicals in the brain. It does not prevent migraines.
- How it’s given: Typically as tablets (often 5 mg or 10 mg). You take it at the onset of a migraine and may repeat once after at least 2 hours if symptoms persist. Maximum daily dose is usually 30 mg (no more than 2 doses in 24 hours).
- Who should avoid or use with caution: People with certain heart or blood vessel problems (e.g., ischemic heart disease, stroke, uncontrolled hypertension), severe liver impairment, or who are taking ergot drugs or MAO inhibitors. Be cautious if also taking other drugs that raise serotonin (to reduce risk of serotonin syndrome).
- Common side effects: Dizziness, sleepiness, fatigue, nausea, dry mouth, or a sensation of pressure or heaviness in the chest. Seek medical care if you have chest pain, severe shortness of breath, or signs of an allergic reaction.
- Pregnancy and children: Rizatriptan is generally categorized as pregnancy category C; use only if clearly needed and prescribed. In children, dosing and approval vary by age and weight; follow a clinician’s instructions.

If you’re considering rizatriptan benzoate, talk with a healthcare provider about your medical history, current medications, and whether it’s appropriate for you. If you’re currently taking other migraine meds or have heart or liver problems, you’ll need tailored advice.