Lipitor is a commonly prescribed medication for high cholesterol, but one of its side effects is exercise fatigue. This can be managed by making certain lifestyle changes and by talking to a doctor about adjusting the dosage or switching to a different medication.

According to a study published in the National Center for Biotechnology Information [2], exercise fatigue is a common side effect of statins like Lipitor. This occurs because statins interfere with the body's production of coenzyme Q10 (CoQ10), which is essential for energy production in the muscles. As a result, patients may experience muscle weakness, pain, and fatigue during exercise.

The Mayo Clinic [3] suggests several ways to manage Lipitor-related exercise fatigue. First, patients should talk to their doctor about their symptoms and whether they can adjust the dosage or switch to a different medication. Second, patients can try taking CoQ10 supplements, which may help alleviate some of the symptoms. Third, patients should make sure to warm up properly before exercising and to start with low-intensity activities before gradually increasing the intensity. Fourth, patients should avoid overexerting themselves and should take breaks as needed.

It is important to note that exercise is still important for overall health, even if it may be more challenging for those taking Lipitor. Patients should work with their doctor to find a balance between managing their symptoms and maintaining an active lifestyle.

Sources:
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949584/
[3] https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013