How much does a dupixent shot cost?

A single Dupixent (dupilumab) shot in the United States typically costs about $1,600 – $2,000 before insurance. That’s the wholesale price that most pharmacies pay and what insurers usually reimburse. Because Dupixent is a specialty biologic, the out‑of‑pocket cost can vary widely depending on:

| Factor | What it does |
|--------|--------------|
| Insurance coverage | Most commercial plans cover Dupixent, but you’ll likely have a copay, coinsurance, or a deductible that can range from a few dollars to over a thousand dollars. |
| Manufacturer assistance | Regeneron’s “Dupixent Patient Assistance Program” can help eligible patients who are uninsured or have high out‑of‑pocket costs. |
| State programs | Some state Medicaid plans cover Dupixent, often with lower copays. |
| Pharmacy benefit manager (PBM) | PBM contracts can influence the patient cost, sometimes lowering it if you use a preferred pharmacy or network. |
| Out‑of‑pocket maximum | If you have high‑deductible health plans, you may hit your yearly out‑of‑pocket cap sooner, after which the insurer covers 100 %. |

If you’re considering Dupixent, it’s a good idea to:

1. Check your insurance plan – look up the drug’s formulary status and any prior‑authorization requirements.
2. Ask your provider – they can request the “step therapy” and insurance pre‑authorization, which can reduce the cost.
3. Contact the patient assistance program – you can apply online or call to see if you qualify.
4. Ask your pharmacist – they can sometimes provide a cost‑share estimate or help navigate copay cards.

In short, a single injection is roughly $1,600–$2,000, but your actual bill can be much lower—or, if you’re uninsured, it could be the full wholesale price. If you’d like help estimating your specific out‑of‑pocket cost, I can guide you through the steps or direct you to the resources you’ll need.