When combining Advil (ibuprofen) with Selective Serotonin Reuptake Inhibitors (SSRIs), there may be an increased risk of certain side effects. According to Drugs.com, concurrent use of these two types of medications can lead to an increased risk of stomach and intestinal ulcers, as well as bleeding [1]. Additionally, the combination may affect the kidneys, leading to decreased kidney function or kidney damage [1].

SSRIs are a class of drugs commonly used to treat depression, anxiety, and other mental health disorders. They work by increasing the levels of serotonin, a neurotransmitter in the brain, which helps regulate mood. Advil, on the other hand, is a non-prescription nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever [2].

It is important to note that the risk of these side effects may vary depending on several factors, including the specific SSRI and Advil dosages, the duration of use, and individual patient characteristics [1]. Patients should consult with their healthcare provider before combining these medications, as they may need to adjust the dosage or monitor for potential side effects [1].

In summary, when mixing Advil and SSRIs, there is an increased risk of stomach and intestinal ulcers, bleeding, and kidney damage. Patients should consult with their healthcare provider before combining these medications, as they may need to adjust the dosage or monitor for potential side effects.

Sources:
[1] <https://www.drugs.com/drug-interactions/ibuprofen-and-selective-serotonin-reuptake-inhibitors-ssris-13-13-151-533-1175-0/>
[2] <https://www.drugpatentwatch.com/drugs/advil>