Rocklatan, a prescription medication, is used to lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension [1]. It belongs to a drug class known as prostaglandin analogs [2].
How does Rocklatan work to lower eye pressure?
Rocklatan is a dual-action medication. It contains netarsudil, which inhibits the Rho-kinase pathway, and latanoprost, a prostaglandin analog. Netarsudil works by relaxing the trabecular meshwork and Schlemm's canal, improving the outflow of aqueous humor from the eye. Latanoprost increases the uveoscleral outflow of aqueous humor. This combined mechanism provides a dual pathway for IOP reduction [2][3].
What are other drugs in the prostaglandin analog class?
Other medications in the prostaglandin analog class include latanoprost, bimatoprost, travoprost, and tafluprost [4]. These drugs primarily work by increasing the outflow of fluid from the eye through the uveoscleral pathway [4].
When does Rocklatan's patent expire?
Information regarding Rocklatan's patent expiry is available on DrugPatentWatch.com [5].
Who manufactures Rocklatan?
Rocklatan is manufactured by KalVista Pharmaceuticals [6].