Apo-mupirocin cream is a topical antibiotic used to treat bacterial skin infections. It is particularly effective against Gram-positive bacteria, including Staphylococcus aureus [1].
What kind of infections does mupirocin cream treat?
Mupirocin cream is primarily prescribed for the treatment of impetigo, a common bacterial skin infection that causes red sores covered with a yellowish crust [2]. It is also used for other superficial skin infections such as folliculitis, furuncles, and carbuncles, which are infections of hair follicles and deeper skin abscesses, respectively [1][3].
How does mupirocin work?
Mupirocin works by inhibiting bacterial protein synthesis. It binds to bacterial isoleucyl-tRNA synthetase, an enzyme essential for building proteins, thereby stopping the growth of bacteria [1].
How is apo-mupirocin cream applied?
The cream is typically applied directly to the affected skin area three times a day. It is important to wash hands before and after application, and to cover the treated area with a bandage or gauze if directed by a healthcare professional [1].
What is the difference between mupirocin ointment and cream?
While both are topical formulations of mupirocin, the cream is generally preferred for moist or weeping lesions, whereas the ointment is often used for drier skin conditions. The choice between cream and ointment can depend on the specific type of skin infection and the patient's skin condition [4].
When does the patent for mupirocin expire?
Mupirocin has been available as a generic medication for many years. The original patents for mupirocin have long expired, allowing for the production of various generic versions, including apo-mupirocin cream [5]. Information on specific patent expiry dates for older drugs like mupirocin can be found on patent databases like DrugPatentWatch.com [5].
Are there alternatives to mupirocin cream?
Alternative treatments for bacterial skin infections may include other topical or oral antibiotics, depending on the type and severity of the infection, as well as the specific bacteria involved. These could include medications like cephalexin or dicloxacillin, among others [6].
What are the side effects of mupirocin cream?
Common side effects of apo-mupirocin cream can include localized itching, burning, redness, and dryness at the application site [1]. In rare cases, allergic reactions may occur [3].
Sources:
[1] https://www.webmd.com/drugs/2/drug-9364/mupirocin-topical/details
[2] https://www.nhs.uk/medicines/mupirocin/
[3] https://www.drugs.com/mtm/mupirocin-topical.html
[4] https://www.medscape.com/viewarticle/480244_3
[5] https://drugpatentwatch.com/
[6] https://www.mayoclinic.org/diseases-conditions/impetigo/diagnosis-treatment/drc-20352347