Sugammadex (generic) – Rough Cost Estimates (United States)
| Package (typical) | Approx. Cost (USD) | Notes |
|-------------------|-------------------|-------|
| 200 mg vial (80 mL) – 2.5 mg/mL | $250 – $350 | Most U.S. pharmacy pricing data (2024) for a generic brand; prices can swing with pharmacy contracts and insurance coverage. |
| 100 mg vial (40 mL) – 2.5 mg/mL | $125 – $175 | Often sold in halves; cost roughly halves, but not exactly linear because of fixed dispensing fees. |
| 400 mg vial (160 mL) – 2.5 mg/mL | $500 – $650 | Larger vials are less common but may be used in high‑dose or long‑duration surgeries. |
Key Points
1. Generic vs. Brand – The original brand name, ALEXION (by Pfizer), has a retail price of roughly $350–$450 per 200 mg vial. Once a generic manufacturer enters the market, the price typically drops by 20–40 %, giving the figures above.
2. Insurance & PBMs – In the U.S., most commercial plans cover sugammadex as a specialty drug, and Pharmacy Benefit Managers (PBMs) often negotiate discounts that can reduce the patient copay to a few dollars or to a “no‑cost” tier for high‑dose indications.
3. Availability – As of 2024, the generic has been approved in the U.S. and Canada but may not yet be stocked by every pharmacy. If a pharmacy does not carry a generic, it will dispense the brand‑name product.
4. International Prices – In the UK, for instance, the NHS price for a 200 mg vial is about £140–£170 (≈ $190–$230). In Australia, the cost per vial is around AUD 220–AUD 280 (≈ $160–$200 USD).
5. Dosage & Cost per Dose – The actual cost you pay depends on the dose required (e.g., 2 mg/kg for reversal of rocuronium). For a 70‑kg patient, the dose is 140 mg; that would be roughly 70 % of a 200 mg vial, so the cost would be about $180–$250, depending on the pharmacy’s pricing schedule.
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How to Find the Exact Cost
- Check your pharmacy: Ask the dispensing pharmacist for the out‑of‑pocket cost for the generic.
- Use price‑comparison tools: Websites like GoodRx, RxSaver, or the Pharmacy Benefit Manager portal for your insurance can show real‑time prices.
- Ask your provider: Some surgeons and anesthesiologists have preferred vendors that can offer volume discounts.
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Bottom Line
Generic sugammadex is typically $250–$350 per 200 mg vial in the United States, which is roughly 20–30 % cheaper than the brand name. Prices can vary widely by location, pharmacy, and insurance plan. Always verify the exact cost with your pharmacy or insurer before the procedure.