What side effects can Aleve (naproxen) tablets cause?
Aleve tablets contain naproxen, a nonsteroidal anti-inflammatory drug (NSAID). Common side effects can include stomach-related effects such as indigestion, heartburn, nausea, and abdominal pain. Some people also get headaches, dizziness, or feel drowsy.
Who is more likely to get serious side effects?
Risk goes up with higher doses and longer use, but certain groups need extra caution:
- People with a history of stomach ulcers or gastrointestinal bleeding
- People taking other medicines that increase bleeding risk (for example, some blood thinners or other NSAIDs)
- People with kidney disease, dehydration, or reduced fluid intake
- Older adults
- People with uncontrolled high blood pressure or certain heart conditions
What serious side effects should you watch for?
Seek urgent medical care if you notice signs of serious problems, including:
- GI bleeding: black/tarry stools, vomiting blood, or severe stomach pain
- Allergic reaction: swelling of the face or throat, trouble breathing, or widespread hives
- Heart or stroke warning signs: chest pain, sudden weakness, trouble speaking, or sudden shortness of breath
- Kidney problems: little or no urination, unusual swelling, or unexplained fatigue
- Liver problems: yellow skin/eyes, dark urine, or severe nausea/vomiting
- Severe skin reactions: blistering or peeling rash
How do Aleve side effects compare with other NSAIDs?
Like other NSAIDs, naproxen can cause stomach irritation and raise cardiovascular and kidney risks. Individual tolerance varies, so switching NSAIDs does not always eliminate side effects—dose and duration still matter.
Can Aleve interact with other medications?
NSAID side effects and bleeding risks can worsen with certain combinations. Tell a clinician/pharmacist about anything you take, especially:
- Blood thinners (for example, warfarin)
- Antiplatelet drugs (for example, clopidogrel)
- Other NSAIDs or aspirin products
- Steroids (for example, prednisone)
- Some antidepressants (SSRIs/SNRIs)
- Lithium, methotrexate, or certain blood pressure medicines (NSAIDs can affect levels and kidney function)
What should you do if you get side effects?
If the effects are mild (like indigestion), taking it with food and avoiding extra NSAIDs may help, but stop and get medical advice if symptoms persist or worsen. Stop using Aleve and seek urgent care for the warning signs listed above.
Pregnancy and breastfeeding: does Aleve have extra concerns?
NSAID use during pregnancy—especially later in pregnancy—can carry risks. If you’re pregnant, trying to conceive, or breastfeeding, it’s important to ask a clinician before using Aleve.
Alternatives if Aleve doesn’t agree with you
If NSAIDs cause stomach or bleeding problems, some people switch to acetaminophen (Tylenol) for pain or ask about other options with lower GI risk. A clinician can help choose based on your medical history and the condition being treated.
Sources
No sources were provided with your question, so I can’t cite specific references.