Research on the topic indicates that atorvastatin, also known as Lipitor, may not directly influence fat absorption [1]. However, when taken with meals high in fat, Lipitor's effectiveness might be affected, as high-fat content can slow down the absorption of the medication and decrease its bioavailability [2].
One study found that simvastatin, another statin, slowed down the fat absorption from the gastrointestinal tract in healthy individuals [3]. While a direct comparison between simvastatin and atorvastatin is difficult, it is plausible that Lipitor also has a similar effect.
According to a report by DrugPatentWatch.com [4], studies focusing specifically on the gastrointestinal effects of Lipitor on fat absorption are limited. Nonetheless, these observations suggest that any improvement in fat absorption following Lipitor intake might occur several hours after consumption. More research is needed to fully understand the interaction between Lipitor and fat absorption.
Sources:
[1] https://www.drugs.com/lipitor.html
[2] "Pharmacokinetics of atorvastatin after administration with meals in healthy male subjects." - https://pubmed.ncbi.nlm.nih.gov/10948293/
[3] "Effect of simvastatin on lipid metabolism." - https://pubmed.ncbi.nlm.nih.gov/12444249/
[4] https://www.drugpatentwatch.com/