Breztri is a prescription inhaled medicine for COPD. It contains three active drugs in one inhaler:
- Budesonide (an inhaled corticosteroid)
- Glycopyrronium (a long-acting antimuscarinic, LAMA)
- Formoterol (a long-acting beta-agonist, LABA)
What it’s used for
- Maintenance treatment to reduce COPD flare-ups (exacerbations) in adults.
- Not for relief of acute wheezing or as an asthma medicine.
How to use (basic guidance)
- Dosing: usually two inhalations twice daily (morning and evening, about 12 hours apart).
- It’s a maintenance inhaler, not a rescue inhaler.
- Follow the exact technique in the patient information leaflet or as your clinician showed you (involves breathing out, sealing lips around the mouthpiece, inhaling slowly, and holding your breath briefly).
What to expect
- Benefits: fewer COPD exacerbations, improved breathing for many patients.
- Onset: can take days to weeks to notice improvement; continue as prescribed.
Common side effects
- Colds or upper respiratory infections
- Cough, throat irritation
- Nasal stuffiness
- Headache
- Possible throat or oral candidiasis (mouth/throat thrush)
Serious considerations (talk to your doctor if you have any of these)
- Increased risk of pneumonia in COPD patients using inhaled steroids
- Shakiness, increased heart rate, or palpitations (from the formoterol/LABA component)
- Worsening breathing problems or severe allergic reactions (rare)
- Not for use in asthma or for relief of an acute attack
- Caution in people with certain heart, blood pressure, or eye conditions (e.g., glaucoma)
Who shouldn’t use it
- Hypersensitivity to budesonide, glycopyrronium, formoterol, or any ingredient in the inhaler
- Not approved for asthma or acute bronchospasm
Notes and tips
- Check the exact excipients (some inhalers contain lactose). If you have a milk protein allergy, verify with your clinician or the product label.
- Do not exceed the recommended dose.
- If you miss a dose by a significant amount, take it as soon as you remember unless it’s nearly time for the next dose; don’t double-dose.
- Tell your healthcare provider about all medicines you take (including other COPD meds), especially other beta-agonists, anticholinergics, steroids, or heart medicines.
If you’d like, tell me your country, whether you’ve been prescribed Breztri and any health conditions you have. I can tailor the indications, dosing, and safety info to your specific situation, or pull up the exact patient information for you.