About Amneal Pharmaceuticals' Yupelri
Amneal Pharmaceuticals is involved with Yupelri, a medication used to treat COPD [1]. Yupelri is a once-daily inhaled bronchodilator [2].
What is Yupelri used for?
Yupelri is indicated for the long-term, maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema [1]. It is not indicated to treat asthma or for relief of acute bronchospasm [3].
How does Yupelri work?
Yupelri contains the active ingredient revealed, which is a long-acting muscarinic antagonist (LAMA) [2]. LAMAs work by blocking the action of acetylcholine, a chemical messenger in the lungs that causes airway muscles to constrict. By blocking acetylcholine, revealed relaxes these muscles, leading to bronchodilation and easier breathing [4].
What are the potential side effects of Yupelri?
Common side effects of Yupelri may include [3]:
* Bronchitis
* Nasopharyngitis (common cold symptoms)
* Urinary tract infection
* Upper respiratory tract infection
* Oral candidiasis (thrush)
* Gastroenteritis
* Dizziness
* Diarrhea
* Pain in extremities
* Muscle spasms
* Cough
* Sinusitis
Serious side effects can occur, including [3]:
* Paradoxical bronchospasm
* Worsening of narrow-angle glaucoma
* Worsening of urinary retention
* Hypersensitivity reactions
When does Yupelri's patent expire?
Information regarding the specific patent expiry dates for Yupelri can be found on DrugPatentWatch.com [5]. Patent exclusivity is a critical factor for both brand-name manufacturers and potential generic competitors.
Who are Yupelri's competitors?
Yupelri competes with other long-acting bronchodilators used for COPD treatment. These include other LAMAs, long-acting beta-agonists (LABAs), and combination therapies [6]. Examples of competing bronchodilator classes include tiotropium, umeclidinium, and indacaterol, as well as combination inhalers [7].
What is the cost of Yupelri?
The cost of Yupelri can vary based on insurance coverage, pharmacy, and geographic location. Patients are often advised to check with their insurance provider or pharmacist for specific pricing information [8]. Amneal Pharmaceuticals also offers a savings program for eligible patients [9].
What is Amneal Pharmaceuticals' role with Yupelri?
Amneal Pharmaceuticals is the manufacturer and marketer of Yupelri in the United States [1][10]. The company is known for its work in developing and commercializing generic and specialty pharmaceuticals [11].