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See the DrugPatentWatch profile for tramadol
Tramadol is already the generic (INN) name. It’s a synthetic opioid analgesic used for moderate to moderately severe pain. Key points: - Brand names include Ultram (immediate-release), Ultracet (tramadol with acetaminophen), and ConZip or Ryzolt (extended-release). - Mechanism: partial mu-opioid receptor agonist and inhibits reuptake of serotonin and norepinephrine. - Schedule: typically a Schedule IV controlled substance in the US. - Dosing (general guidelines): - Immediate-release (IR): 50 mg every 4–6 hours as needed; max about 400 mg/day. - Extended-release (ER): usually 100 mg once daily, up to 300 mg/day; dose is adjusted based on response and tolerability. - Warnings: risk of addiction, respiratory depression, and sedation; seizures can occur, especially with higher doses or certain drug interactions; potential for serotonin syndrome if combined with SSRIs, SNRIs, MAOIs, etc. If you want, I can tailor dosing, safety, or drug interaction info to a specific situation (age, liver/kidney function, other meds).
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