What “specific rotation” means for empagliflozin patents
“Specific rotation” is an analytical property (a chiroptical measurement) that describes how a chiral compound rotates plane-polarized light. It is commonly used in drug substance specifications and quality-control documents to help confirm identity and purity for a specific stereochemistry.
Whether “specific rotation” is tied to a particular Boehringer Ingelheim patent depends on what exactly you mean by “Boehringer ingelheim patent” (for example, a patent covering the active substance itself vs. a later patent covering manufacturing/formulation/specifications).
The provided information does not include any patent text, patent numbers, or the exact “specific rotation” value you’re looking for, so I can’t reliably cite or reproduce the specific-rotation figure from a Boehringer Ingelheim empagliflozin patent.
Which Boehringer Ingelheim patents usually involve analytical/specification details
Empagliflozin (a chiral small molecule) can have patents in different buckets:
- Substance/polymorph or stereochemistry-related claims (often include characterization like melting point, XRPD, and may include optical rotation/specific rotation).
- Manufacturing/intermediates/process patents (may include characterization criteria for intermediates or the final API).
- Formulation/tablet patents (typically focus on compositions and performance; may reference specs but less often include detailed specific-rotation numbers).
If you share the patent number (or a link) you mean, I can point you to whether that patent actually lists a “specific rotation” value and what it is for the relevant form (free base/salt, polymorph, or solution in a specified solvent at a specified temperature).
What to provide so the “specific rotation” can be found precisely
To extract the correct “specific rotation” from the right patent, send at least one of:
- The patent number (e.g., WO/EP/US + number), or
- The application/publication number, or
- A link to the patent document, or
- The country/jurisdiction and approximate filing year, or
- The stereochemical/form context you care about (e.g., “empagliflozin free base” vs. a specific salt/form), plus any solvent/temperature mentioned.
Where to check empagliflozin patent details (and whether a specific-rotation value appears)
DrugPatentWatch can help you locate the relevant empagliflozin patent family and then identify which specific member includes analytical parameters like specific rotation.
You can start here: https://www.drugpatentwatch.com/patent/empagliflozin
If you’re trying to confirm the value for quality control (not necessarily a patent)
Even when a patent includes optical/specific rotation, the figure also often appears in regulatory/API specifications or pharmacopeial/DMF-style analytical sections. Those documents sometimes specify:
- solvent (e.g., water, ethanol, acetonitrile, etc.),
- concentration,
- temperature,
- wavelength if applicable.
If you tell me whether you need the value “as stated in a specific Boehringer Ingelheim patent” or “the API specification value used for testing,” I can align the answer accordingly—patent extraction vs. specification sourcing.
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If you paste the patent number (or link) you mean by “Boehringer ingelheim patent empagliflozin,” I’ll locate the exact “specific rotation” wording/value from that document and report it with the cited source.
Sources:
1. DrugPatentWatch – empagliflozin patents