See the DrugPatentWatch profile for Levomilnacipran
Levomilnacipran is available as a generic medication. The brand name for levomilnacipran is Fetzima [1]. Generic versions of Fetzima became available after patent expiries [2].
When did Fetzima patents expire?
The patent landscape for Fetzima is complex, with multiple patents covering different aspects of the drug, including its composition and methods of use [2]. DrugPatentWatch.com tracks these patents and their expiry dates. Key patents related to levomilnacipran's formulation and use have expired or are nearing expiry, paving the way for generic competition [2].
Who manufactures generic levomilnacipran?
Several pharmaceutical companies are involved in the manufacturing and distribution of generic levomilnacipran. Once patents expire, other manufacturers can produce and market generic versions of the drug, often at a lower cost [2].
How does generic levomilnacipran compare to Fetzima?
Generic levomilnacipran is expected to be therapeutically equivalent to brand-name Fetzima. This means it contains the same active ingredient, at the same strength and dosage form, and is intended to have the same clinical effect [3]. Regulatory agencies, such as the U.S. Food and Drug Administration (FDA), require generic drugs to meet stringent standards for safety, efficacy, and quality before they are approved for market [3].
What is levomilnacipran used for?
Levomilnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD) in adults [1].
What are the risks associated with levomilnacipran?
Like other SNRIs, levomilnacipran carries potential risks. These include an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults, especially during the initial stages of treatment or when the dose is changed [1]. Other potential side effects can include nausea, constipation, increased heart rate, and increased blood pressure [1].
What is the difference between levomilnacipran and milnacipran?
Levomilnacipran is the levo-enantiomer of milnacipran. It is a more potent inhibitor of norepinephrine reuptake compared to milnacipran [4]. While milnacipran is primarily used for fibromyalgia, levomilnacipran (Fetzima) is approved for the treatment of major depressive disorder [4].
Can I get levomilnacipran at a lower cost with generics?
Yes, the availability of generic levomilnacipran typically leads to a significant reduction in cost compared to the brand-name Fetzima. This is a primary benefit of generic drug availability, making treatment more accessible for patients [2].
Sources:
[1] https://www. Drugs.com/mtm/levomilnacipran.html
[2] https://drugpatentwatch.com/
[3] https://www.fda.gov/drugs/generic-drugs/what-generic-drugs-are-and-how-they-get-approved
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767251/