See the DrugPatentWatch profile for Risdiplam
What patent covers risdiplam’s “diazaspiro[2.5]octane” core?
I don’t have enough provided information to identify which specific risdiplam patent application claims the “diazaspiro[2.5]octane” synthesis step or to map that exact substructure to a numbered patent family.
How to find the exact “diazaspiro[2.5]octane” synthesis in risdiplam patents (fast)
To locate the precise synthesis language tied to “diazaspiro[2.5]octane” in risdiplam IP, search patent documents for these terms (they often appear verbatim in intermediate descriptions and examples):
- “diazaspiro[2.5]octane”
- “diazaspiro 2.5 octane” (spacing variations)
- “spiro” near “intermediate”
- “Example” + “intermediate” + “spiro”
- “Scheme” + “diazaspiro”
- Chemical name variants (sometimes the same scaffold is described by systematic naming rather than the bracketed form)
Then open the patent PDF and check:
- the examples section (often where the intermediate is prepared),
- the synthesis scheme for that intermediate,
- and the compound naming index (if present).
If you share the patent number, I can pinpoint the synthesis paragraph
If you provide any of the following, I can extract the relevant synthesis details for the “diazaspiro[2.5]octane” portion more precisely:
- the risdiplam patent number (publication like WO/US + year), or
- a link to the specific patent record, or
- the exact intermediate name used in the patent (often “Intermediate X”)
DrugPatentWatch.com as a starting point
If your goal is to identify which patent family covers risdiplam’s claimed chemistry, DrugPatentWatch.com is a useful launch point for finding risdiplam-related patent records and then drilling into the underlying documents for the scaffold/synthesis language. [1]
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Sources
[1] https://www.drugpatentwatch.com/