Based on the information provided, I was unable to find specific data on how often Lipitor affects protein creation. However, I can provide some context on Lipitor and its interaction with the body.

Lipitor, also known as atorvastatin, is a statin medication used to treat high cholesterol levels. It works by inhibiting HMG-CoA reductase, an enzyme that plays a crucial role in the production of cholesterol in the body [1]. By reducing cholesterol levels, Lipitor helps prevent plaque buildup in the arteries, thus lowering the risk of heart attacks and strokes.

While Lipitor's primary mechanism of action is related to cholesterol synthesis, there is some evidence suggesting that statins like Lipitor may have pleiotropic effects, which include modulation of protein expression and function [2]. However, the specific impact on protein creation and the frequency of such events are not well-defined in the available literature.

In summary, while Lipitor does not directly target protein creation as its primary function, there is some evidence suggesting that it may have secondary effects on protein expression. More research is needed to determine the frequency and specifics of these interactions.

Sources:

1. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063091>
2. Fazio, S., & Lüscher, T. F. (2010). Pleiotropic Effects of Statins. Circulation, 122(22), 2245–2247. <https://doi.org/10.1161/CIRCULATIONAHA.110.961233>
3. DrugPatentWatch. (n.d.). Lipitor (Atorvastatin) Drug Patent Expiration & Generic Launch Dates. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>