PreVymis is a vaccine indicated for the active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 17F, 19A, 19F, and 22F in individuals 6 weeks of age and older [1]. It is a pneumococcal 20-valent conjugate vaccine [1].
Who makes PreVymis?
PreVymis is manufactured by Pfizer Inc. [1].
How does PreVymis work?
PreVymis contains purified capsular polysaccharides from 20 Streptococcus pneumoniae serotypes conjugated to a carrier protein [1]. Upon administration, the vaccine elicits an immune response that helps the body develop antibodies against these specific serotypes of pneumococcal bacteria, thereby protecting against invasive disease [1].
What is the dosage for PreVymis?
The recommended dosing schedule for PreVymis depends on the age of the individual. For infants 6 weeks through 6 months of age, the primary series consists of three 0.5 mL doses administered at 2, 4, and 6 months of age. A fourth dose is recommended at 12 through 15 months of age [1]. For individuals 7 months of age and older who have not been previously vaccinated, the dosing schedule varies based on age group, often involving one or two doses [1].
What are the potential side effects of PreVymis?
The most common side effects observed in clinical trials for PreVymis in infants and children included irritability, decreased appetite, drowsiness, rash, fever, and injection site pain [1]. In adults, common side effects included injection site pain, fatigue, headache, muscle pain, joint pain, and decreased appetite [1].
How does PreVymis compare to other pneumococcal vaccines?
PreVymis offers broader serotype coverage compared to some other pneumococcal vaccines. It protects against 20 serotypes, including serotype 3, which is a leading cause of pneumococcal disease, and several other common and emerging serotypes [1]. This expanded coverage aims to address a wider range of pneumococcal bacteria strains that can cause invasive disease [1].
When does PreVymis patent expire?
Information regarding specific patent expiry dates for PreVymis is not readily available in the provided text. DrugPatentWatch.com is a resource that tracks pharmaceutical patents and exclusivity [2].