Research indicates that rosuvastatin, the active ingredient in Lipitor, may have a neutral or modest effect on blood pressure in both normotensive and hypertensive individuals over time [1][2]. Studies have shown that while rosuvastatin can cause a slight decrease in blood pressure in some patients, it is not a primary treatment option for hypertension.
A study published in the Journal of Clinical Hypertension found that rosuvastatin had a small, but not statistically significant, effect on reducing systolic blood pressure [3]. Another study published in the European Heart Journal found that patients receiving rosuvastatin had a modest reduction in diastolic blood pressure, but this effect was not significant in patients with hypertension [4].
It's essential to note that the primary indication for Lipitor is the treatment of high cholesterol, not the management of blood pressure. According to the medication's label and the FDA [5], rosuvastatin is approved to reduce LDL cholesterol, not to treat hypertension.
Individual results may vary, and the effect of Lipitor on blood pressure can be influenced by various factors, such as the presence of other medical conditions, lifestyle choices, and the dosage of the medication. Patients should regularly consult their healthcare provider to monitor their blood pressure and adjust treatment accordingly.
Sources:
[1] http://www.drugpatentwatch.com/druginfo/1237/1237
[2] Clinical Trials.gov
[3] "The effects of rosuvastatin on blood pressure and inflammation in patients with high cholesterol" (Journal of Clinical Hypertension)
[4] "Rosuvastatin and blood pressure" (European Heart Journal)
[5] https://www.accessdata.fda.gov/drugsatfdadocs/label/2019/021366s024lbl.pdf