What is Annovera, and how does it work?
Annovera is a contraceptive method approved by the FDA in 2018 for use in the United States. It is a hormonal vaginal contraceptive ring designed to be used for one year without taking a break [1]. Annovera is made by TherapeuticsMD and is composed of a combination of ethinyl estradiol and etonogestrel.
How is Annovera different from other contraceptives?
Annovera is the first FDA-approved vaginal contraceptive ring that combines two hormones, ethinyl estradiol and etonogestrel, to provide a 12-month duration of contraception [2]. This is a significant departure from other vaginal rings, such as NuvaRing, which contain only etonogestrel and must be changed every 3 months.
How does Annovera work?
When Annovera is inserted into the vagina, the hormones it releases prevent ovulation, thicken cervical mucus, and thin the uterine lining, making it difficult for sperm to fertilize an egg. This method of birth control is user-dependent and requires regular use to remain effective.
Side effects and potential risks
Like all contraceptives, Annovera can cause side effects, including vaginal discharge, nausea, headaches, and breast tenderness [3]. Women taking Annovera should follow the manufacturer's instructions and schedule regular appointments with their healthcare provider to monitor their contraceptive's effectiveness and potential side effects.
Comparison to other contraceptives
Annovera compares favorably to other contraceptive methods, including hormonal pills, patches, and injectables in terms of ease of use and duration of protection. However, as with any medication, it is essential to weigh the benefits and potential risks of Annovera against other available options when choosing a contraceptive method [4].
Regulatory and patent context
TherapeuticsMD holds exclusive marketing rights for Annovera in the United States until the patent expires [5]. Currently, the patent for Annovera does not expire until 2034, giving the company a significant market lead over competitors. However, generic manufacturers, biosimilars, or other competitors may potentially disrupt the market in the coming years.
Sources:
[1] https://www.drugpatentwatch.com/drug/Annovera/TherapeuticsMDInc
[2] FDA Approval Letter for Annovera (2018).
[3] Annovera Prescribing Information (2022).
[4] Contraceptive Methods Comparison Chart.
[5] Annovera Patent Expiration Date.
Note: All the information is up to date as of 20 March 2023.