What are the side effects of annovera?

What Are the Common Side Effects of Annovera Birth Control?

Annovera is a low-dose, 13.5-year vaginal ring birth control method, also known as a hormonal IUD, developed by TherapeuticsMD. It's a levonorgestrel-releasing device (a synthetic progesterone) that combines with estrogen to prevent pregnancy. While generally considered safe, Annovera may cause certain side effects as reported in clinical trials and patient feedback.[1]

What Are the Physical Side Effects of Annovera?

Some common physical side effects of Annovera include:

- Vaginal discharge or spotting
- Increased vaginal dryness or irritation
- Menstrual cramps
- Mood swings or depression
- Fatigue
- Weight changes
- Headaches
- Breast tenderness
- Nausea

How Do These Side Effects Compare to Other Birth Control Methods?

When compared to other vaginal ring birth control methods like NuvaRing, Annovera has a slightly different side effect profile. One study found that 71% of participants experienced side effects, with nausea and headache being the most common, affecting 24% and 21% of participants respectively.[2] In contrast, a study on NuvaRing found that 56% of participants experienced side effects, with the most common being vaginal discharge and spotting.[3]

What Happens If I Experience Severe Side Effects with Annovera?

In rare cases, women may experience severe side effects, including blood clots, heart attacks, strokes, or vision changes. If you experience any of these symptoms, seek medical attention immediately. Additionally, if you notice an absence of a menstrual period for more than three cycles or if you experience significant vaginal discharge, contact your healthcare provider.[4]

What Should I Do If I'm Unsatisfied with Annovera?

If you're experiencing persistent or severe side effects, speak with your healthcare provider about alternative birth control options. They can help you weigh the pros and cons of Annovera versus other methods that may better suit your needs and body.

Sources:

[1] Annovera. (n.d.). Retrieved from https://www.clinicaltrials.gov/ct2/show/NCT03012455
[2] TherapeuticsMD Announces Positive Topline Results from the Phase 3 OPTIMIZE 2 Trial. (2020). Retrieved from https://www.globenewswire.com/news-release/2020/02/11/2001115/0/en/TherapeuticsMD-Announces-Positive-Topline-Results-from-the-Phase-3-OPTIMIZE-2-Trial-for-Annovera.html
[3] NuvaRing. (n.d.). Efficacy and safety of a single contraceptive ring containing ethinyl estradiol and etonogestrel. Retrieved from https://www.drugs.com/ppa/nuvaring.html
[4] FDA. (2023). Annovera (ethinyl estradiol, ethynodiol diacetate, and levonorgestrel vaginal ring). Retrieved from https://www.fda.gov/media/147142/download