The question at hand is whether antidepressant users should adjust their Advil (ibuprofen) intake. To answer this question, it is important to understand how antidepressants and Advil may interact with each other.

Antidepressants are a common treatment for depression and anxiety disorders, and they work by affecting the levels of certain chemicals in the brain [2]. On the other hand, Advil is a non-prescription medication used to relieve pain, reduce inflammation, and bring down a fever [1].

According to the Mayo Clinic, there are generally no specific interactions between Advil and antidepressants that would require a dosage adjustment [3]. However, it is important to note that some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), can increase the risk of bleeding when taken with Advil [3]. Therefore, it is always advisable to consult with a healthcare provider before taking any medication, including Advil, while on antidepressants.

It is also important to follow the recommended dosage for both antidepressants and Advil, as taking too much of either medication can lead to serious health consequences. Additionally, mixing antidepressants with other substances, such as alcohol or illegal drugs, can also be dangerous and should be avoided [2].

In summary, while there are no specific interactions between Advil and antidepressants that would require a dosage adjustment, it is always important to consult with a healthcare provider before taking any medication while on antidepressants. It is also crucial to follow the recommended dosage for both antidepressants and Advil and avoid mixing them with other substances.

Sources:

* <https://www.drugpatentwatch.com/p/tradename/ADVIL>
* <https://www.nhs.uk/mental-health/talking-therapies-medicine-treatments/medicines-and-psychiatry/antidepressants/considerations/>
* <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970>