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Ozempic (semaglutide) doesn’t have a separate dose for “insulin sensitivity.” The dosing is for glycemic control in type 2 diabetes (and can help with weight loss, which may improve insulin sensitivity indirectly). The typical titration is: - Start: 0.25 mg subcutaneous once weekly for 4 weeks - Then: 0.5 mg once weekly (if tolerated) - If needed after at least 4 weeks on 0.5 mg: increase to 1 mg once weekly - If still not at goal after at least 4 weeks on 1 mg: increase to 2 mg once weekly (maximum) Take on the same day each week. If you miss a dose, take it as soon as you remember and resume your regular weekly schedule; don’t double up doses. Important safety notes: - Ozempic is not for type 1 diabetes or diabetic ketoacidosis. - Do not use if you have a personal or family history of medullary thyroid carcinoma or MEN2. - Common side effects include nausea, vomiting, diarrhea, and decreased appetite; GI symptoms often lessen with continued use. - Tell your doctor about other meds and any history of pancreatitis or gallbladder disease; avoid if pregnant or breastfeeding unless advised by a clinician. If you’re considering Ozempic specifically to improve insulin sensitivity, it may not be the right approach for everyone. A clinician can tailor the dose and discuss alternatives (e.g., lifestyle changes, metformin, etc.). Want me to help you think through how this fits with your medical context?
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