| Intended Use |
Basal‑bolus replacement therapy for type 2 diabetes when oral agents or basal insulin alone are insufficient. |
| Typical Starting Dose |
0.2–0.4 units/kg body weight, divided 70 % basal (glargine) and 30 % bolus (lispro). |
| Administration |
Subcutaneous injection once daily, usually at the same time each day. Common sites: abdomen, thigh, or upper arm. |
| Timing |
Can be given in the evening or early morning; insulin lispro is meant to cover meals, so it should be administered within 30 minutes before or after eating. |
| Monitoring |
Blood glucose at least twice daily (fasting and post‑meal). Adjust dose based on glucose patterns and HbA1c. |
| Typical Dose Range |
20–80 units/day, but varies widely; titration is individualized. |
| Common Adverse Effects |
Hypoglycaemia (most common), injection‑site reactions (pain, redness, swelling). |
| Less Common |
Edema, weight gain, rare allergic reactions. |
| Contraindications |
Hypersensitivity to any component of Soliqua, type 1 diabetes (unless used as part of a basal‑bolus regimen under specialist care). |
| Warnings & Precautions |
• Use with caution in renal or hepatic impairment.
• Monitor for hypoglycaemia in elderly, patients with reduced food intake, or those on other hypoglycaemic agents.
• Pregnancy: insulin is the preferred agent; use as directed by a healthcare provider. |
| Drug Interactions |
• Caffeine and alcohol can blunt hypoglycaemic effect.
• Other antidiabetic agents may increase hypoglycaemia risk. |
| Storage |
Store in refrigerator (2–8 °C). After first use, can be kept at room temperature (up to 30 °C) for up to 28 days. Protect from light. |
| Disposal |
Follow local regulations for sharps; use puncture‑resistant containers. |
| Patient Education Points |
1. Check blood glucose before the first dose each day.
2. Watch for symptoms of low or high blood sugar (sweating, shakiness, confusion, blurred vision, or extreme thirst and urination).
3. Rotate injection sites to avoid lipodystrophy.
4. Keep a log of doses, meals, and glucose readings. |