Save time and get answers to complex questions with AI chat
Lipitor vs generics what's the price gap?Somatuline depot patent expiry date?Combivent inhaler hfc 152a patents?What is dabrafenib mesylate msn patent issue?Pramlintide approval date?
Soliqua 100/33 is a prescription fixed-dose injectable medicine for adults with type 2 diabetes. It combines two active ingredients in one pen: - Insulin glargine, 100 units/mL (a long-acting basal insulin) - Lixisenatide, 33 mcg/mL (a GLP-1 receptor agonist) What it’s used for - To improve glycemic control in adults with type 2 diabetes when a GLP-1 receptor agonist and a basal insulin are appropriate to use together as a single daily injection. How to use (general guidelines) - Dose form: once daily subcutaneous injection, ideally within 1 hour before the first meal of the day. - Starting dose: usually 15 units per day (which corresponds to 15 units insulin glargine and about 5 mcg lixisenatide per dose). - Titration: can increase by 2–4 units every 3–4 days to reach your glucose goals. - Maximum: the recommended maximum daily dose is 60 units (which will also deliver up to about 20 mcg lixisenatide per day). - Do not split dosing or use more than one dose per day. Important precautions and contraindications - Do not use if you have had medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). - Not for people with type 1 diabetes or diabetic ketoacidosis. - Warnings include risk of pancreatitis with GLP-1 receptor agonists, potential thyroid C-cell tumors (including in animals), gallbladder problems, and possible hypoglycemia when used with other diabetes medicines. - Tell your healthcare provider about all medications you take (especially other diabetes medicines like sulfonylureas or other insulins) since hypoglycemia risk can increase. Common side effects - Nausea, vomiting, diarrhea, or decreased appetite (common with GLP-1 therapies) - Injection-site reactions - Possible weight change - Hypoglycemia can occur, especially if you’re also using other glucose-lowering medicines Administration and safety tips - Rotate injection sites (abdomen, outer thigh, or upper arm) to reduce skin irritation. - Do not inject into the same exact spot repeatedly. - Use a new needle for each injection and do not share pens. - Store the pen as directed (typically refrigerated before first use; follow label instructions for after initial use). - If you miss a dose, contact your clinician for guidance on re-dosing. Who to talk to - Always consult your doctor or a pharmacist for advice tailored to your situation, especially about dosing if you’re switching from another insulin regimen or have kidney issues, are pregnant, or have a history of pancreatitis or thyroid disease. If you’d like, I can pull up the official prescribing information or provide a patient-friendly summary specific to your situation (e.g., what to do if you’re currently on basal insulin, how to titrate, or potential drug interactions). Do you want that?
Other Questions About Soliqua :