Trulance (pralusetib) is a prescription medication used to treat adults with inadequately controlled moderate to severe irritable bowel syndrome with diarrhea (IBS-D) [1]. It is also approved for adults with chronic idiopathic constipation (CIC) [1].
How Does Trulance Work?
Trulance is a guanylate cyclase-C (GC-C) agonist [1]. In the gastrointestinal tract, it stimulates the secretion of chloride and bicarbonate into the intestinal lumen through an increase in cyclic guanosine monophosphate (cGMP) [1]. This leads to increased fluid secretion and accelerated intestinal transit [1].
Where Can I Learn About Trulance's Availability and Pricing?
Information regarding purchasing Trulance online should be sought from legitimate online pharmacies or through your healthcare provider [1]. It is a prescription medication, meaning a valid prescription from a licensed healthcare professional is required for purchase [1]. For current pricing and availability, consulting directly with pharmacies or checking insurance coverage details is recommended.
What Are the Potential Side Effects of Trulance?
The most common side effect of Trulance is diarrhea [1]. Other potential side effects include nausea, abdominal pain, and flatulence [1]. Patients experiencing severe or persistent diarrhea, or any other concerning side effects, should contact their doctor immediately [1].
What Should I Consider Before Taking Trulance?
Before starting Trulance, it is important to discuss your medical history with your doctor, especially if you have any heart problems, liver problems, or are pregnant or breastfeeding [1]. Inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements [1].
Are There Alternatives to Trulance for IBS-D or CIC?
Yes, there are other medications available for the treatment of IBS-D and CIC. These may include other GC-C agonists, lubiprostone, or linaclotide, depending on the specific condition and patient needs [2]. Lifestyle changes, such as dietary adjustments and stress management, can also play a role in managing these conditions [2].
Sources
1. Trulance. https://www.trulance.com/
2. DrugPatentWatch.com. (n.d.). Trulance (Pralusetib) Information. https://drugpatentwatch.com/