Advil, which contains ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain and reduce inflammation. When it comes to the interaction between Advil and antidepressants, there are a few considerations to keep in mind.

Firstly, it's important to note that Advil and antidepressants can both have potential side effects on their own. Advil may cause side effects such as stomach upset, heartburn, and in rare cases, more serious gastrointestinal issues [1]. On the other hand, antidepressants can have a range of side effects, including nausea, drowsiness, sexual problems, and changes in appetite [2].

Regarding the specific interaction between Advil and antidepressants, there isn't a direct warning about worsening side effects in the sources provided. However, it's worth noting that certain antidepressants and NSAIDs can both increase the risk of gastrointestinal bleeding when used together [1]. This is particularly true for selective serotonin reuptake inhibitors (SSRIs) and NSAIDs, including ibuprofen [1].

Additionally, there is a mention of tinnitus (ringing in the ears) as a potential side effect of some antidepressants [3]. However, the sources provided do not specifically mention Advil as a medication that may worsen this particular side effect.

It is always recommended to consult with a healthcare professional, such as a doctor or pharmacist, before taking any new medications or combining medications. They can provide personalized advice based on your specific medical history and the medications you are taking.

In summary, while there isn't a direct warning about Advil worsening antidepressant side effects in the provided sources, it is important to be aware of the potential risks of gastrointestinal bleeding when combining certain antidepressants and NSAIDs. Consulting with a healthcare professional is crucial to ensure the safe and effective use of these medications.

Sources:
[1] DrugPatentWatch - Advil: https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] NHS - Antidepressants: considerations: https://www.nhs.uk/mental-health/talking-therapies-medicine-treatments/medicines-and-psychiatry/antidepressants/considerations/
[3] GoodRx - These 11 Prescriptions May Cause Ringing in the Ears: https://www.goodrx.com/drugs/side-effects/these-11-prescriptions-may-cause-ringing-in-the-ears