What patents cover daridorexant synthesis, and what do they usually claim?
Patents that describe “daridorexant synthesis” typically claim one or more of the following: the preparation of key intermediates, the coupling/reaction sequence that forms the daridorexant core, purification steps (salt formation, crystallization), and specific reaction conditions (reagents, catalysts, temperatures, solvents, and purification methods). These claims are often tied to commercial drug substance manufacturing, not the final drug product tablet/capsule.
If you are looking for a specific synthesis-process patent, the most relevant filings are usually in the patent families for:
- Daridorexant (active pharmaceutical ingredient) manufacture (drug substance)
- The “intermediate” used to assemble the final molecule
- Crystalline forms or salt forms (which can include process-related steps)
Where to find the exact “synthesis process” patent documents
The fastest way to identify the correct patent documents is to search by:
- The generic name: “daridorexant” plus “process” / “preparation” / “manufacturing” / “intermediate”
- The compound’s chemical descriptors (IUPAC name) plus “process” / “synthesis”
- Applicant/assignee names tied to daridorexant development and manufacturing
Common places to search:
- Google Patents (broad search and citation linking)
- The patent office for the jurisdiction you care about (USPTO, EPO, JPO, etc.)
- WIPO Patentscope for international (PCT) families
How to search better when you only know “daridorexant”
Because some patents won’t say “daridorexant” in the title, searches often need to use both:
- “daridorexant” and process terms (for example: “daridorexant” AND “preparation”)
- “intermediate” terms plus the relevant step language (for example: “intermediate” AND “reaction”)
- Assignee keywords (for example, searching the assignee name plus “daridorexant process”)
If you share any of the following, I can help narrow down the exact patent family members to check:
- jurisdiction (US/EU/JP/KR/CN, etc.)
- applicant/assignee name
- any patent number you’ve seen
- whether you mean “drug substance synthesis” or “crystal/salt formation”
What synthesis-process patents might NOT include (important scope issue)
Even if a patent is about “daridorexant synthesis,” it may not give a complete step-by-step procedure for every stage of manufacture. Some filings focus on:
- only one intermediate or one key transformation (partial process)
- only the purification/crystallization (form and yield optimization)
- only the method for a specific stereochemical step (chiral intermediate formation)
So “synthesis process patent” can mean different levels of detail. The best match is usually the one that explicitly claims a multi-step manufacturing method or a complete preparation route to the drug substance.
Are there formulation patents mixed into synthesis-process searches?
Yes. Results can include:
- tablet/capsule formulation patents (excipients, coating, dissolution)
- device or dosing regimen patents
- crystalline form patents (which sometimes include process conditions)
These are different from pure synthesis-process claims. Filtering by keywords like “intermediate,” “preparation,” “manufacture,” and “reaction” helps.
If you want freedom-to-operate: what to check beyond synthesis
If your goal is to avoid infringement, synthesis patents are only one piece. You also check:
- drug substance composition/impurity patents
- crystalline form or salt form patents (if your product uses a specific form)
- method-of-use patents (less relevant for manufacturing but still important)
- jurisdiction-specific status (grants, continuations, and whether claims were narrowed)
Next step: I can pinpoint the right patent docs if you provide one missing detail
Right now, “Daridorexant synthesis process patent” is too broad to name a specific document family or patent number from the information provided. Tell me either:
1) the jurisdiction you care about (US/EU/JP/etc.), or
2) the patent/assignee name you’ve seen, or
3) the exact wording from the search result (title snippet or publication number),
and I’ll guide you to the most likely matching synthesis-process patents and what each one claims.