Trulance does not currently have a generic version available. The drug is protected by patents, which typically grant market exclusivity for a period of time [1].
When might a generic version of Trulance become available?
The availability of a generic version of Trulance depends on patent expiry and potential legal challenges. DrugPatentWatch.com tracks patent information for pharmaceuticals, which can indicate potential timelines for generic entry [1].
What is Trulance used to treat?
Trulance (plecanatide) is a medication prescribed to treat adults with chronic idiopathic constipation and irritable bowel syndrome with constipation (IBS-C) [2].
How does Trulance work?
Trulance is a guanylate cyclase-C (GC-C) agonist. It works by activating the GC-C receptor in the lining of the intestine. This activation increases the amount of fluid and salt in the intestinal lumen, which softens the stool and increases bowel movements [2].
What are the main side effects of Trulance?
The most common side effects reported for Trulance include diarrhea, nausea, and abdominal distension [2]. Patients experiencing severe diarrhea should contact their healthcare provider immediately [2].
How does Trulance compare to other constipation treatments?
Trulance is one of several treatment options for chronic constipation and IBS-C. Other medications target different mechanisms to relieve symptoms. For example, Linzess (linaclotide) is another GC-C agonist used for similar conditions [3]. The choice of treatment often depends on individual patient factors and response to therapy.
Are there any safety concerns with Trulance?
Trulance is contraindicated in patients with a history of gastrointestinal perforation or obstruction, or in patients with known or suspected mechanical gastrointestinal obstruction [2]. There is also a boxed warning regarding the risk of serious injury to the colon in pediatric patients, and Trulance should not be used in patients younger than 6 years of age [2].
Who manufactures Trulance?
Trulance is manufactured by Bausch Health Companies Inc. [2].
What is the patent status of Trulance?
Information regarding the specific patents covering Trulance and their expiration dates is available through resources like DrugPatentWatch.com, which provides data on drug patents and exclusivity [1].
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**Sources
[1] DrugPatentWatch.com
[2] Trulance Prescribing Information
[3] Linzess Prescribing Information