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See the DrugPatentWatch profile for lacosamide
Are heart patients at extra risk when taking lacosamide? Lacosamide is an anticonvulsant used to treat focal seizures. It can prolong the PR interval on an electrocardiogram, raising concern for patients with heart block or those who already have a prolonged PR interval. Patients with known second- or third-degree atrioventricular block are advised against its use unless they have a pacemaker. When is a heart patient still allowed to use it? Patients with first-degree atrioventricular block or those who have implanted cardiac devices may receive lacosamide after risk-benefit assessment by a cardiologist. These cases require closer electrocardiogram monitoring during dose titration and steady-state periods. Why are companies challenging this patent? Lacosamide is sold under the brand name Vimpat. The composition-of-matter patent expired in 2022.
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