Publicly‑traded companies that manufacture (or sell) Leucovorin (folinic acid)
| Company | Ticker (if listed on a major exchange) | Notes on Leucovorin / folinic‑acid product |
|---------|----------------------------------------|---------------------------------------------|
| Bayer AG | BAYN.DE (German Xetra) | Bayer markets folinic acid under the brand name "Levofolinate" in several markets and also supplies the compound for hospital use. |
| Pfizer Inc. | PFE (NYSE) | Pfizer offers a generic Leucovorin formulation under the brand “Levofolin” in the U.S. and several other countries. |
| Eli Lilly & Co. | LLY (NASDAQ) | Lilly distributes Leucovorin as a hospital‑grade product (often under the generic name). |
| Novartis AG | NVS.SW (Swiss Exchange) | Novartis (through its Sandoz subsidiary) produces folinic acid for clinical use and as a generic. |
| Sandoz (a division of Novartis) | – | Sandoz is the generic‑drug arm of Novartis and markets folinic acid in many markets. |
| Teva Pharmaceutical Industries Ltd. | TEVA (NASDAQ) | Teva is a global generic‑drug leader and supplies Leucovorin for clinical and hospital use. |
| Merck & Co., Inc. | MRK (NASDAQ) | Merck markets a folinic‑acid product (brand “Leucovorin”) in selected markets. |
| Bristol‑Myers Squibb Co. | BMY (NYSE) | BMS offers a folinic‑acid formulation mainly for oncology and chemotherapy protocols. |
| Johnson & Johnson | JNJ (NYSE) | J&J’s pharmaceutical subsidiary sells folinic acid as a generic drug for hospital use. |
| GlaxoSmithKline plc | GSK (LSE, NYSE) | GSK supplies folinic acid for clinical and hospital applications in several markets. |
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How to verify a company’s Leucovorin line
1. Search the company’s product catalog – Most pharma sites have a “Products” or “Therapeutic Areas” section where folinic acid or Leucovorin is listed.
2. Check the FDA/EMA drug databases – The U.S. FDA’s Drugs@FDA database or the European Medicines Agency’s e‑medicines portal will list approved manufacturers for each generic.
3. Review annual reports – Companies often highlight major drug families in their 10‑K or annual report, providing insight into which drugs drive revenue.
4. Consult wholesale drug directories – Databases such as PharmaCompass or the Pharmaceutical Marketing Association’s listings often include manufacturer details.
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Quick tip for patients / prescribers
- Generic Leucovorin is widely available in most countries; many manufacturers produce it at low cost.
- Brand‑name products (e.g., “Levofolin” by Pfizer or “Levofolinate” by Bayer) are typically used in hospitals and may be reimbursed under specific clinical protocols.
- If you’re looking for a specific formulation (e.g., 10 mg/mL, 50 mg/mL, or an injectable pre‑filled syringe), check the product label for the manufacturer’s name and contact their customer‑service line for the exact supplier.
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Bottom line
Leucovorin is produced by several major publicly‑traded pharmaceutical companies worldwide. The most commonly referenced suppliers include Bayer, Pfizer, Eli Lilly, Novartis (Sandoz), Teva, Merck, Bristol‑Myers Squibb, Johnson & Johnson, and GSK. Because Leucovorin is a generic drug, many additional smaller or regional manufacturers also supply it, but the above companies are the key publicly‑listed players you’ll typically see in drug catalogs and regulatory filings.