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How does a high fat diet reduce lipitor s effectiveness?

See the DrugPatentWatch profile for lipitor

A high-fat diet may reduce the effectiveness of Lipitor, a medication commonly prescribed to lower cholesterol levels. Lipitor, also known as atorvastatin, works by reducing the production of cholesterol in the body [1]. However, consuming a high-fat diet can increase the levels of low-density lipoprotein (LDL), or "bad" cholesterol, in the blood [2].

When a high-fat diet is consumed, the liver increases its production of LDL in order to transport the excess fat. This can counteract the effects of Lipitor, which is designed to decrease LDL levels. As a result, the medication may be less effective in individuals who consume high-fat diets [3].

It is important to note that while a high-fat diet can reduce the effectiveness of Lipitor, it is not the only factor that can impact the medication's efficacy. Other factors, such as genetics, lifestyle habits, and the presence of other medical conditions, can also affect how well Lipitor works [4].

In summary, a high-fat diet can reduce the effectiveness of Lipitor by increasing the levels of LDL in the blood, which can counteract the medication's intended effects. It is important for individuals taking Lipitor to follow a healthy diet and lifestyle in order to maximize the medication's effectiveness.


1. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <>
2. American Heart Association. (2021). What Your Cholesterol Levels Mean. Retrieved from <>
3. (2021). Lipitor. Retrieved from <>
4. (2021). Lipitor (Atorvastatin Calcium). Retrieved from <>

Other Questions About Lipitor :  Can i trust lipitor generics given fda approval? Any residual effects from lipitor? Is it risky to mix lipitor and alcohol for the liver?

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