Lurbinectedin is a chemotherapy drug used to treat certain types of cancer, including small cell lung cancer and ovarian cancer. According to the sources provided, there are several side effects associated with the use of lurbinectedin.

The first source [1] explains that the most common side effects of lurbinectedin include fatigue, nausea, vomiting, decreased appetite, and constipation. Other side effects that may occur include low white blood cell count, anemia, and increased liver enzymes. These side effects may vary in severity depending on the individual and the dose of the drug.

The second source [2] provides more detailed information about the potential side effects of lurbinectedin. In addition to the common side effects mentioned above, the drug may also cause hair loss, mouth sores, diarrhea, and fever. More serious side effects that may occur include infections, bleeding, and heart problems. Patients may also experience allergic reactions to the drug, which can cause difficulty breathing, swelling, and rash.

The third source [3] provides a case report of a patient who experienced severe side effects after receiving lurbinectedin treatment. The patient developed acute liver failure and required a liver transplant as a result of the drug's toxicity. While this is a rare occurrence, it highlights the potential risks associated with the use of lurbinectedin.

In conclusion, lurbinectedin is associated with several side effects, ranging from mild to severe. Patients receiving this drug should be monitored closely for any signs of adverse reactions and should report any symptoms to their healthcare provider immediately. It is important for patients to discuss the potential risks and benefits of lurbinectedin with their healthcare provider before starting treatment.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LURBINECTEDIN
[2] https://www.mayoclinic.org/drugs-supplements/lurbinectedin-intravenous-route/side-effects/drg-20490804?p=1
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165873/