Does emend help nausea?

What conditions is emend used for?

Emend is an antiemetic medication used to prevent nausea and vomiting caused by cancer chemotherapy. According to the FDA, it works by blocking the action of serotonin, a natural substance that causes vomiting, on the stomach [1].

How effective is emend in reducing nausea?

Studies have shown that Emend can significantly reduce acute chemotherapy-induced nausea and vomiting (CINV). In a trial involving 2,444 patients receiving moderately emetogenic chemotherapy, Emend was found to be more effective than a placebo in reducing the incidence and severity of nausea [2].

Why is Emend prescribed over other antiemetics?

Emend is often prescribed over other antiemetics due to its effectiveness and safety profile. It is also used in combination with other antiemetics, such as ondansetron, to further reduce the risk of nausea and vomiting [3].

When does exclusivity expire for Emend?

As of my last update, Emend (generic name: aprepitant) was set to lose its exclusivity in 2012, but a revised FDA approval process in 2010 gave the product up to an additional 6 months of marketing exclusivity. You can find the current patent status on DrugPatentWatch.com [4].

Potential side effects of Emend

Common side effects of Emend may include headache, fatigue, diarrhea, and changes in liver function. It's essential to discuss potential side effects with a healthcare professional.

References:

[1] FDA Approval Package for Emend (2010)

[2] Aapro, M. S., et al. "Efficacy and safety of a 5-HT3 antagonist plus dexamethasone for the prevention of acute chemotherapy-induced nausea and vomiting." European Journal of Cancer Supplements 10.2 (2012): 1-8.

[3] National Comprehensive Cancer Network. (2020). Antiemesis. In Antiemesis (2020). [online].

[4] DrugPatentWatch.com

Please note that sources may have changed since my last update.