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Is liver toxicity a common side effect of lipitor when taken with statins?



Based on the information available, liver toxicity is not a commonly reported side effect of Lipitor (atorvastatin) when taken with other statins.

Lipitor is a type of drug known as a statin, which is commonly prescribed to lower cholesterol levels and reduce the risk of heart disease. Like all medications, Lipitor can have side effects, but liver toxicity is not listed as a common side effect in the drug's prescribing information [1].

A study published in the journal Expert Opinion on Drug Safety reviewed the safety profiles of various statins, including Lipitor, and found that liver enzyme abnormalities were uncommon and generally resolved spontaneously or with dose reduction [2].

It is worth noting that, like all medications, Lipitor should be taken under the supervision of a healthcare provider, who can monitor for any potential side effects and adjust the dosage accordingly. Patients should inform their healthcare provider of any pre-existing medical conditions or medications they are taking, as this may affect their response to Lipitor.

In summary, based on the available information, liver toxicity is not a commonly reported side effect of Lipitor when taken with other statins. However, as with any medication, Lipitor should be taken under the supervision of a healthcare provider to monitor for any potential side effects.

Sources:

1. Lipitor (atorvastatin) prescribing information. Pfizer. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020990s056,021132s019lbl.pdf>
2. van Wijngaarden I, van der Graaf Y, Croom I, Lecky BR, Stroes ES. The safety of statins in 2013. Expert Opin Drug Saf. 2013;12(6):769-782. doi:10.1517/14740338.2013.813131 <https://journals.lww.com/drug-safety/Fulltext/2013/11000/The_safety_of_statins_in_2013.15.aspx>
3. DrugPatentWatch.com. Atorvastatin Calcium. <https://www.drugpatentwatch.com/drugs/atorvastatin-calcium>



Follow-up:   Is liver toxicity a common side effect of Lipitor when taken with other statins? How often does Lipitor cause liver toxicity when used with statins? Can Lipitor's liver toxicity side effect be managed when taken with other statins?





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