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Lipitor lowers LDL cholesterol by blocking an enzyme in the liver that makes cholesterol. Patients taking Lipitor typically see LDL drops of 20 to 60 percent, depending on the dose. Can Lipitor also raise good cholesterol? Lipitor does raise HDL cholesterol by 5 to 9 percent on average, but the effect is smaller than its action on LDL. Some patients see no change or even a slight drop in HDL. What happens to triglyceride levels? Lipitor reduces triglyceride levels by 10 to 30 percent. This action occurs alongside the main LDL-lowering effect and happens at all approved doses. When does Lipitor start working? Most patients see cholesterol changes within two weeks of starting Lipitor, with full effects reached by four to six weeks. Doctors usually recheck labs at six to 8 weeks to adjust the dose if needed. How does Lipitor compare with other statins? Lipitor is classified as a moderate- to high-intensity statin. It provides stronger LDL lowering than simvastatin and lovastatin at comparable doses, but comparable effects to rosuvastatin and pravastatin at adjusted doses.
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