Phexxi is a novel vaginal gel contraceptive designed to prevent pregnancy. It works by creating an acidic environment in the vagina that is hostile to sperm [1].
How does Phexxi work to prevent pregnancy?
Phexxi's mechanism of action involves lowering vaginal pH, making it difficult for sperm to survive and reach an egg. The active ingredients, lactic acid, citric acid, and potassium bitartrate, work together to achieve this acidic pH [1].
What are the active ingredients in Phexxi?
The active ingredients in Phexxi are lactic acid, citric acid, and potassium bitartrate [1]. These components are responsible for lowering the vaginal pH.
How is Phexxi used?
Phexxi is inserted into the vagina using an applicator, similar to how tampons or menstrual cups are used. It is intended for use before sexual intercourse. The gel is designed to remain effective for a specific period after insertion, with instructions provided for optimal use [1].
What is the effectiveness rate of Phexxi?
In clinical trials, Phexxi demonstrated a 86% effectiveness rate with typical use, meaning that 14 out of 100 women using Phexxi for a year became pregnant [1]. With perfect use, the effectiveness rate increased to 93%, indicating that 7 out of 100 women using Phexxi perfectly for a year became pregnant [1].
What are the potential side effects of Phexxi?
Common side effects reported with Phexxi include vaginitis, vulvovaginal discomfort, and urinary tract infection [1].
Can Phexxi be used with other birth control methods?
Phexxi is a standalone contraceptive and is not intended for use with other birth control methods [1].
Who manufactures Phexxi?
Phexxi is manufactured by Evofem Biosciences [1].
What are the alternatives to Phexxi?
Various contraceptive options are available, including hormonal methods like birth control pills, patches, and rings, as well as long-acting reversible contraceptives (LARCs) such as IUDs and implants. Barrier methods like condoms and diaphragms, as well as permanent sterilization, are also alternatives [1].
When was Phexxi approved?
Phexxi was approved by the U.S. Food and Drug Administration (FDA) in December 2019 [1].