Diltiazem is available in generic forms. The original brand name for diltiazem was Cardizem [1].
When does diltiazem patent expire?
The original patents for diltiazem have long expired, allowing for the development and sale of generic versions. This is typical for older drugs that have been on the market for a significant period [2]. DrugPatentWatch.com tracks patent expiration dates for pharmaceuticals.
How does generic diltiazem work?
Generic diltiazem, like its brand-name counterpart, is a calcium channel blocker. It works by relaxing the muscles of the heart and blood vessels, which leads to a decrease in heart rate and blood pressure [3]. This action helps to treat conditions such as hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders [4].
What are the different forms of diltiazem available?
Diltiazem is available in various formulations, including immediate-release tablets, extended-release capsules, and intravenous injections [5]. Generic versions are typically manufactured to be bioequivalent to the brand-name drug, meaning they deliver the same amount of active ingredient into the bloodstream over the same period [6].
Who makes generic diltiazem?
Numerous pharmaceutical companies manufacture generic versions of diltiazem. These companies must meet strict quality and manufacturing standards set by regulatory bodies like the U.S. Food and Drug Administration (FDA) [7].
How does generic diltiazem compare to brand-name Cardizem?
Generic diltiazem is chemically identical to brand-name Cardizem and is expected to have the same therapeutic effect [6]. The primary differences often lie in the inactive ingredients (fillers, binders, etc.), which can sometimes affect tolerability in a small number of individuals, and the cost, with generics generally being significantly less expensive [7].
What are the side effects of diltiazem?
Common side effects of diltiazem can include dizziness, headache, nausea, and swelling of the ankles or feet [8]. More serious, though less common, side effects can involve slow heart rate, heart block, or liver problems [9]. Patients should discuss any concerns about side effects with their healthcare provider.
Where can I find more information on diltiazem patents?
Information on drug patents, including diltiazem, can be found on specialized resources such as DrugPatentWatch.com, which provides detailed data on patent status and expiration for a wide range of medications [2].
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Sources:
[1] https://www.drugpatentwatch.com/drug/diltiazem
[2] https://www.drugpatentwatch.com/
[3] https://www.nhs.uk/medicines/diltiazem/
[4] https://www.mayoclinic.org/drugs-supplements/diltiazem-oral-capsule-extended-release-oral-tablet-oral-tablet-extended-release-intravenous-route/proper-use/drg-20072570
[5] https://medlineplus.gov/druginfo/meds/a682062.html
[6] https://www.fda.gov/drugs/generic-drugs/what-generic-drugs-are-approved-fda
[7] https://www.fda.gov/drugs/generic-drugs
[8] https://www.mayoclinic.org/drugs-supplements/diltiazem-oral-capsule-extended-release-oral-tablet-oral-tablet-extended-release-intravenous-route/side-effects/drg-20072570
[9] https://www.drugs.com/sfx/diltiazem-side-effects.html